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Available: Yes* |
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Edition: | 1st |
Publisher: | Academic Press, Incorporated |
ISBN: | 0-12-817310-6 (0128173106) |
ISBN-13: | 978-0-12-817310-7 (9780128173107) |
Binding: | E E Book + ProQuest Ebook Central |
Copyright: | 2019 |
Publish Date: | 08/19 |
Volume: | 14 |
Weight: | 0.00 Lbs. |
Subject Class: | GEN (Genetics) |
Remarks: | A New Edition of this title is due 03/25 |
Return Policy: | Non-Returnable. |
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ISSN Series: | Translational Epigenetics | Discipline: | Biochemistry | Subject Definition: | Epigenomics; Nutrigenomics | NLM Class: | QU 45 | LC Class: | QP144 | Abstract: | Over the last decade, interest in diet-gene interactions has led researchers to examine epigenomic reprogramming and nutritional intervention in the treatment and prevention of disease. These studies, in part assisted with technological advances in epigenomic sequencing, have increased our understanding of diet's influence over epigenetic regulation in aging, fetal growth and development, transgenerational inheritance, and circadian rhythm, in addition to health and disease. Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, and current understanding of nutrition's role in epigenomic regulation of disease, health, and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet's role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are discussed as well, as are the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors also examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. Throughout Nutritional Epigenomics, close attention is paid not only to recent findings of translational significance, but epigenomic approaches, technologies, and modes of analysis to enable future epigenomic studies Fully empowers the reader in employing nutritional epigenomics approaches in their own researchDiscusses the latest topics in nutritional epigenomics in regulation of aging, circadian rhythm, inheritance and fetal development, as well as metabolism and diseaseOffers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies |
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