Animal and Translational Models for CNS Drug Discovery: Reward Deficit Disorders

McArthur, Robert A. PhD

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Book Information
Edition:	1st
Publisher:	Academic Press, Incorporated
ISBN:	0-12-373860-1 (0123738601)
ISBN-13:	978-0-12-373860-8 (9780123738608)
Binding:	Hardcover
Copyright:	2008
Publish Date:	10/08
Volume:	3
Weight:	2.20 Lbs.
Pages:	383
Carton Quantity:	18
Subject Class:	PRM (Pharmacology)
Return Policy:	Returns accepted up to 90 days provided no other recalls or return restrictions apply.
Table Of Contents:	View
Contributing Authors:	View
ProQuest Ebook Central:	Available in ProQuest Ebook Central™ View

Class Specifications
Discipline:	Pharmacology
Subject Definition:	Disease Models, Animal; Drug Design
NLM Class:	QV 744
LC Class:	RM301.25
Abstract:	The use of appropriate models can minimize the number of drug candidates that later fail in human trials by accurately predicting the efficacy and the toxicity of each compound. This can be improved with more informed selection of the appropriate models. This book provides disorder-specific guidelines to selecting the appropriate non-human models for trials in the drug discovery and development process. Reward Deficit Diseases is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for reward deficit disorders such as nicotine abuse and alcoholism. Each chapter focuses on the translational issues surrounding each reward deficit disorder with connections between the use of animal models and human clinical trials. This is the third volume in the three-volume set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, and is also available for purchase individually.