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Gestational Trophoblastic Disease: Diagnostic and Molecular Genetic Pathology

Hui, Pei
Gestational Trophoblastic Disease: Diagnostic and Molecular Genetic Pathology Cover Image
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Book Information
Edition: 1st
Publisher: Humana Press
ISBN: 1-61779-394-9 (1617793949)
ISBN-13: 978-1-61779-394-3 (9781617793943)
Binding: E E Book + ProQuest Ebook Central
Copyright: 2012
Publish Date: 12/11
Weight: 0.00 Lbs.
Subject Class: PTH (Pathology)
Remarks:
A New Edition of this title is due 04/25
Return Policy: Non-Returnable.
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Class Specifications
ISSN Series: Current Clinical Pathology
Discipline: Gynecology
Subject Definition: Trophoblastic Neoplasms; Uterine Neoplasms
NLM Class: WP 465
LC Class: RC280
Abstract: In this volume Dr Hui has brought together a comprehensive overview of gestational trophoblastic disease that includes all the currently recognized entities: complete and partial hydatidiform moles, placental site trophoblastic tumor, epithelioid trophoblastic tumor, gestational choriocarcinoma, persistent gestational trophoblastic neoplasia, placental site nodule and exaggerated placental site reaction. Each entity is reviewed in detail, with emphasis on genetic background, clinical presentation, pathologic findings and ancillary studies, differential diagnosis and clinicopathological correlations. Descriptions of the pathology are supported by numerous excellent photomicrographs. Recent advances in our understanding of the genetics of gestational trophoblastic diseases are stressed. Introductory chapters cover the developmental biology of the placenta and the genetic basis of gestational trophoblastic disease, and one chapter is devoted to the molecular diagnosis of gestational trophoblastic disease. This chapter includes a review of the use of short tandem repeat (STR) genotyping which is of particular value in the diagnosis of hydatidiform moles. The final chapter covers clinical aspects of gestational trophoblastic disease, including treatment. The text throughout is current and thoroughly referenced. This book will be of great value to pathologists, community gynecologists, gynecological pathologists and medical students.
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