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Available: Yes* |
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Other formats:
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Edition: | 1st |
Publisher: | Springer Nature |
ISBN: | 981-1304-81-5 (9811304815) |
ISBN-13: | 978-981-1304-81-1 (9789811304811) |
Binding: | E E Book + ProQuest Ebook Central |
Copyright: | 2018 |
Publish Date: | 10/18 |
Weight: | 0.00 Lbs. |
Subject Class: | GEN (Genetics) |
Return Policy: | Non-Returnable. |
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ProQuest Ebook Central�: |
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Discipline: | Biochemistry | Subject Definition: | Genetic Therapy; Cell- and Tissue-Based Therapy | NLM Class: | QU 560 | LC Class: | RB155.8 | Abstract: | Recent advances in stem cell biology, nanotechnology and gene therapy have created new avenues for therapeutics. The availability of molecular therapeutics that rely on delivery of DNA, RNA or proteins, harnessing enhanced delivery with nanoparticles and the regenerative potential of stem cells (adult, embryonic or induced pluripotent stem cells) have made tremendous impact in translational medicine. The proposed book cover the various strategies for molecular and cellular therapies for human disease, their advantages and challenges to their widespread applications. Potential solutions to these issues are also discussed elaborately. This book provides an overview of advances on novel therapeutics that will be of interest to general scientific readership. In addition, the authors provide specific examples of disease conditions where these strategies have been translated to the clinic. A dedicated chapter that deal with viral vectors and analysis of reports from ongoing clinical trials. A separate section on clinical trials involving nanoparticles for gene delivery has also been included. Further the book also pays attention to the hybrid vectors, which are combination of viral and chemical vector; a collaborative therapy involving gene therapies and pharmacologic therapies, etc. Besides the above mentioned areas, the proposed book will also discuss about Aptamers and various types of stem cells for their therapeutic applications. This book is going to be extremely useful for students, researchers, clinicians and scientists working in the field of gene/molecular therapy for various diseases. |
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