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Renin-Angiotensin System: Current Research Progress in The Pancreas: The RAS in the Pancreas
Leung, Po Sing PhD
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Book Information
Edition:
1st
Publisher:
Springer Nature
ISBN:
90-481-9060-6 (9048190606)
ISBN-13:
978-90-481-9060-7 (9789048190607)
Binding:
E E Book + ProQuest Ebook Central
Copyright:
2010
Publish Date:
07/10
Volume:
690
Weight:
0.00 Lbs.
Subject Class:
BCH (Biochemistry)
Return Policy:
Non-Returnable.
Table Of Contents:
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Class Specifications
ISSN Series:
Advances in Experimental Medicine & Biology
Discipline:
Gastroint Sys
Subject Definition:
Renin-Angiotensin Sys-Physiology; Pancreatic Dis-Physiopath
NLM Class:
WI 830
LC Class:
RC857
Abstract:
The human pancreas has vital roles in the regulation of glucose homeostasis and digestion and its dysfunction leads to pancreatic disease as diabetes and pancreatitis. Recent researches have highlighted the novel roles of a local renin-angiotensin system (RAS) in the pancreas and its clinical relevances; its inapprporiate activation leads to pancreatic endocrine and exocrine disease, notably type 2 diabetes. As such, manipulation of the overactive RAS may improve pancreatic islet cell function, cell mass and insulin sensitivity, as well as enhancing the growth and differentiation of pancreatic stem cells. Blockade of the RAS may be protective against pancreatitis and pancreatic cancer. The research outcome of current progress on the RAS in the pancreas should provide an alternative approach to preventing and treating, as well as curing pancreatic disease. This book discusses the progress of research on the renin-angiotensin system in the pancreas from the science to the bedside, providing a timely review of this expanding area. It consists of ten interrelated chapters covering subjects as: . Structure, physiology and disease of the pancreas . Biochemistry and physiology of the pancreatic renin-angiotensin system . RAS in diabetes, stem cells and pancreatitis This book is of special value to basic and clinical scientists, clinicians, graduate students, as well as novices in this field.
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